Antioxidative effect of Royal Jelly
Recent research has confirmed that royal jelly is antioxidative and demonstrated another beneficial application of the compound. Males of reproductive age, from 15-35 years old, face an increased risk of testicular cancer. One of the primary treatment forms has been cisplatin-based (CP) chemotherapy, which can damage healthy cells in the testes and lead to infertility. CP is known to reduce weight of the testes and other male reproductive organs, cause a drop in sperm count, and reduce sperm mobility. These changes are primarily the result of the oxidizing agents released during CP treatment.
Royal Jelly Benefits Counteract CP-induced Damage
Three groups of rats were used to demonstrate the antioxidant capacity of royal jelly. Group one was exposed to CP treatment alone, and group two received both CP chemotherapy in conjunction with royal jelly. All findings were referenced to a control group.
The two experimental groups received a single dose of CP, predictably resulting in lower concentrations of sperm and other effects noted above. A biomarker for oxidative stress, malondialdehyde, was also found in increased concentrations. Group two was fed royal jelly for 10 days and experienced significant reversal of CP-induced damage, resulting in lower levels of malondialdehyde and increase in fertility markers.
Potential Benefits for Cancer Patients
Positive findings have led to increased understanding of royal jelly benefits by expanding applications of its antioxidant value. Reproductive damage in males is often the result of environmental and dietary toxins that generate higher levels of oxidizing agents in the body. Royal jelly is antioxidative due to a combination of compounds, and it has the ability to reverse infertility by neutralizing free radicals.
Though this experiment used CP chemotherapy to create oxidative stress, the results can be generalized to other stress inducers, lending weight to claims that royal jelly can increase fertility in males.
Published: February 1, 2010 in Fertility Weekly Newsletter – FertilityWeekly.com.
Author: S. Suzuki, Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, 5-11-12 Tateishi, Katsushika-ku, Tokyo 124-0012, Japan